Interim data results
Interim data from the FACE cohort seems to confirm these findings1, and provide some positive insights in HFpEF:
- The FACE prospective cohort aimed to provide real-world data about the prognosis of HF patients with CSA treated with ASV. This interim analysis provides some long-term morbidity and mortality data of 391 HF patients (HFrEF, HFmrEF or HFpEF) eligible to ASV therapy followed during 2 years.
- Severe hypoxemia (high T90) during sleep is a strong independent risk factor for mortality in HF patients (HR=12).
- ASV therapy was associated with a better prognosis in CHF patients with severe nocturnal hypoxaemia or non-ischemic etiology, especially in subgroups with middle-range or preserved LVEF but not with reduced LVEF.
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- R Tamisier et al: Late Breaking Abstract – Morbidity and mortality of chronic heart failure (CHF) patients with central sleep apnoea (CSA) treated by adaptive servoventilation (ASV): Interim results of FACE cohort study_Update. ERJ September 2017 Supplement.